Dragon Quest IX: Sentinels of the Starry Skies

System: NDS Publisher: Square Enix Release: 2009/07/11 Lifetime Sales: 4,143,749

Animal Crossing: New Leaf

System: 3DS Publisher: Nintendo Release: 2012/11/08 Lifetime Sales: 4,136,911

Mario Kart DS

System: NDS Publisher: Nintendo Release: 2005/12/08 Lifetime Sales: 3,969,364

Pokemon Heart Gold / Soul Silver

System: NDS Publisher: Pokemon Co. Release: 2009/09/12 Lifetime Sales: 3,910,511

Brain Age: Train Your Brain in Minutes a Day!

System: NDS Publisher: Nintendo Release: 2005/05/19 Lifetime Sales: 3,882,083

Dragon Quest VII: Warriors of Eden

System: PS1 Publisher: Enix Release: 2000/08/26 Lifetime Sales: 3,874,141

Mario Kart Wii

System: WII Publisher: Nintendo Release: 2008/04/10 Lifetime Sales: 3,783,315

Tomodachi Collection

System: NDS Publisher: Nintendo Release: 2009/06/18 Lifetime Sales: 3,736,361

Wii Sports

System: WII Publisher: Nintendo Release: 2006/12/02 Lifetime Sales: 3,705,469

Pokemon Sun / Moon

System: 3DS Publisher: Pokemon Co. Release: 2016/11/18 Lifetime Sales: 3,664,155